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I don't disagree with you, but it does seem like you're using "do the meds work" as the key criteria of whether its a trait or an illness. But I guess I don't understand why that matters, apart from "how should we socially judge this person?" There are a large number of mental and physical illnesses that can be improved (by the judgement of the patient) by a wide range/combination of meds, actions, choices, etc...

If I have schizophrenia and I treat it without meds and I get better, that doesn't prove you wrong. If I treat it exclusively with meds and get better, that doesn't prove Caplan wrong. Because it doesn't matter to me! What matters is: "by my standards and accounting for the cost of treatment, did I get better?" If you want to say "schizophrenia that you can treat without meds doesn't count" then I am 100% fine with that - but I think you (and Caplan) are fighting over definitions instead of reality.

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"Do the meds work" isn't a good criterion for whether something is a disease because 1) many illnesses are untreatable, and 2) you can use drugs to stop non-disease behaviors and preferences easily (chemical castration of homosexuals).

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Agreed, with the addition that may also be an indication that determining if something is a disease or not isn't that helpful (where I define helpful as "helps make the patient better of).

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In my example, the key criteria was "is there an associated common pathway model?"

Whether the meds work or not cannot tell us about whether a trait is real, but it can lend evidence to the idea if we see that there is a treatment effect and it is not heterogeneous (ex: https://jamanetwork.com/journals/jamapsychiatry/article-abstract/2776610). Homogeneous treatment effects are unrealistic for many traits because treatment is generally not targeted at the etiology of a disease comprehensively, so this can only be used to provide positive, not negative evidence wrt whether a psychiatric diagnosis tags an actual trait.

The concerns raised by PercyPrior have to do with measurement invariance, which is often tenuous, rather than etiology, which I was concerned with.

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